Section 14.5 - Fluorescent and Biotinylated Dextrans
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چکیده
Dextrans are hydrophilic polysaccharides characterized by their moderate to high molecular weight, good water solubility and low toxicity. They are widely used as both anterograde and retrograde tracers in neurons 1,2 and for numerous other applications. Dextrans are biologically inert due to their uncommon poly-(α-D-1,6-glucose) linkages, which render them resistant to cleavage by most endogenous cellular glycosidases. They also usually have low immunogenicity. Molecular Probes offers almost 100 fluorescent and biotinylated dextran conjugates in several molecular weight ranges.
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